Cellular Responses to Patterned Poly(acrylic acid) Brushes

Patterned biofunctional poly(acrylic acid) brushes on silicon surfaces.

Protein patterning was carried out using a simple procedure based on photolithography wherein the protein was not subjected to UV irradiation and high temperatures or contacted with denaturing solvents or strongly acidic or basic solutions. Self-assembled monolayers of poly(ethylene glycol) (PEG) on silicon surfaces were exposed to oxygen plasma through a patterned photoresist. The etched regio...

Discriminatory Bio-Adhesion Over Nano-Patterned Polymer Brushes

Patterned Biofunctional Polymer Brushes CNF Project # 640 - 97 Principal Investigator :

Protein patterning was carried out using a simple procedure based on photolithography wherein the protein was not subjected to UV irradiation and high temperatures, or contacted with denaturing solvents, and strongly acidic or basic solutions. Self-assembled monolayers of poly(ethylene glycol) (PEG) on silicon surfaces were exposed to oxygen plasma through a patterned photoresist. The etched re...

Preparation of Micro-Crystalline Cellulose-Reinforced Polyacrylic Acid Hydrogel and its Application in Paper/Polyacrylic Acid Composites

Paper/polyacrylic acid (PAA) composites were prepared using a microcrystalline cellulose (MCC)-reinforced PAA hydrogel. The MCC-reinforced PAA hydrogel was prepared by in-situ UV light-induced polymerization of acrylic acid in the presence of MCC. The experimental results showed that the presence of MCC improved the water absorption capacity of the resulting PAA hydrogel. The addition of 1 wt% ...

Hyaluronic Acid Inhibits Polycation Induced Cellular Responses

Positively charged macromolecules cause a variety of pathological events through their electrostatic interaction with anionic sites present on the membrane of target cells. In the present study we have investigated the effect of hyaluronic acid, a negatively charged molecule, on rat paw oedema induced by poly-L-lysine as well as on histamine release from rat mast cells and nitric oxide formatio...